Identifying Specific Causes of Kidney Allograft Loss
نویسندگان
چکیده
منابع مشابه
Identifying specific causes of kidney allograft loss.
The causes of kidney allograft loss remain unclear. Herein we investigated these causes in 1317 conventional kidney recipients. The cause of graft loss was determined by reviewing clinical and histologic information the latter available in 98% of cases. During 50.3 +/- 32.6 months of follow-up, 330 grafts were lost (25.0%), 138 (10.4%) due to death with function, 39 (2.9%) due to primary nonfun...
متن کاملAbsence of MyD88 signaling induces donor-specific kidney allograft tolerance.
Toll-like receptors (TLRs) play a fundamental role in innate immunity and provide a link between innate and adaptive responses to an allograft; however, whether the development of acute and chronic allograft rejection requires TLR signaling is unknown. Here, we studied TLR signaling in a fully MHC-mismatched, life-sustaining murine model of kidney allograft rejection. Mice deficient in the TLR ...
متن کاملAllograft loss from acute Page kidney secondary to trauma after kidney transplantation
We report a rare case of allograft loss from acute Page kidney secondary to trauma that occurred 12 years after kidney transplantation. A 67-year-old Caucasian male with a past surgical history of kidney transplant presented to the emergency department at a local hospital with left lower abdominal tenderness. He recalled that his cat, which weighs 15 lbs, jumped on his abdomen 7 d prior. On phy...
متن کاملRejection of the kidney allograft.
Copyright © 2010 Massachusetts Medical Society. The science of kidney transplantation has progressed considerably in the past half-century largely because of an improved understanding of the role of the immune system in allograft rejection, the disentanglement of the molecular mechanisms underlying graft failure, and better management of immunosuppression.1,2 Rejection has always been the major...
متن کامل[Causes of death with a functioning graft among kidney allograft recipients].
BACKGROUND Death with a functioning graft (DWGF) is now one of the main causes of renal transplant (RTx) loss. AIM To determine whether the causes of DWGF, characteristics of donors and recipients and complications of RTx have changed in the last two decades. SUBJECTS AND METHODS Cooperative study of a cohort of 418 kidney grafts performed between 1968 and 2010. Patients were divided into t...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2009
ISSN: 1600-6135,1600-6143
DOI: 10.1111/j.1600-6143.2008.02519.x